Your computer MAY need housecleaning.  If you are an AOL user, use their free McAfee Security center to safely clean out your cache, registery, temp files etc and defrag the puppy-especially the cache.  If you don't have it, use the Cleanmgr that comes with Windows.  If you been "working" Poser for several hours, things begin to not work properly -after you have cleaned hourse, do a defrag, then power down the puppy for about 10 seconds.  See if that works.