I set up all my scenes inside Poser before taking them into Vue for rendering, it's a very easy and painless procedure!
As Silverblade says, the set up then in Vue is mainly camera and lighting but obviously there are other things to take into account also.
Vue's lighting and render engine knocks spots off anything Poser can do which is the main reason I use it but by no means the only reason.
For outdoor scenes Vue easily beats Poser also when you can use eco-systems and realistic vistas, it's "simply the best" as Tina Turner would say!!

Injustice will be avenged.
Cofiwch Dryweryn.