No it won't erase your poser content.

However, you need your original serial number in order to get the SR updates for the program.

If you buy a copy of Poser on Amazon, unless it's a brand new boxed version where the serial number has never been used, you won't be able to use it to get the updates from e-Frontier.

My advice is to keep looking for your CD, or contact e-Frontier or Smith Micro and provide them with proof of purchase and see if you can get a download version of the program from them.

"It is good to see ourselves as others see us. Try as we may, we are never
able to know ourselves fully as we are, especially the evil side of us.
This we can do only if we are not angry with our critics but will take in good
heart whatever they might have to say." - Ghandi