Quote - The larger your runtime the longer it will take Poser to start up.

Nothing personal Acadia, I consider you a friend you know that, but I get fed up seeing this one come up all the time, it's an inaccurate statement!!
I have one runtime which is huge set up in sub folders and each week it gets bigger and each week my start up time NEVER gets longer and in fact since going to 64 bit, it's quicker than before.
Start up time depends on a lot more than runtime size, any number of things could cause it to slow down including Viruses, trojans and not defragging often enough!!

Rant over!! 

I'm sorry it's something you find rant worthy but it is a fact. I have over 20 different runtimes and Poser loads faster if the last runtime I accessed is a small one versus a large one. IE: If I close it when the last runtime is the default runtime where I don't install anything, next time I open it it's lighteneing fast. If however, I close Poser while it's accessing the DAZ runtime or my Sci-Fi Runtime, both of which are HUGE, it can take a couple minutes for Poser to open. So Yes Matilda, Size does matter.