Nothing, if you study it for hours and hours.  Someone coming into it cold would have dificulty with it though. As an occasional user, I still have some problems with it  which I might be prone to chalk up to lazyness and lack of research . . . given the compexity of the app though, you'd be crazy to ask for the simplicity of say, Wings.(What's that Bryster? Now, you KNOW I don't share your views on Heresy, so stop it ! ! ) Tell you what - go into Blenders interface and try to make heads or tails of it in under a week.  

A newby would have a lot of trouble finding things in C4D in the same way - for example the Bodypaint menu.  

. . but be that as it may, I've been hoping to see AgentSmith to work with T.S . for what seems two millenia now; as good as he is, we'd all benefit from his experiences with it - providing of course that he posts his findings once in a while. 

Well, it's been a hard day - too much sun and not enough Ovaltine.