I think the problem lies in websites and less to do with what browser you use. Noscript is fantastic - have a browse through the firefox extensions there are loads of useful ones.  Even mainstream legit sites have been hacked recently so its always good to air on the side of caution. Life is easier on other systems (than that of windows because thats the most heavily targeted).  Having used both Macs and windows ( I can duel boot). Windows is scary because you seem to have less control over what happens to your operating system.  I'm running AVG, spybot and spyware doctor and still found ClamX on my mac partition found virueses that the other pc apps didin't which worried me some what.

 I think you've just got to use what ever you can. IE does seem to be targeted as well - general dislike of microsoft in the hacking community - I've known a few in my time!

 Just make sure you keep everything upto date and keep an eye out of forums etc for potential problems. No point bashing other systems - help others - if you hear of a potential problem pass it on to your fellow pc users - the advice that is not the problem!