Poser is just terrified of good video cards is all it is. It's intimidated by power. It was designed in the days when a user was lucky to have an onboard 3dfx card with 32 MB of RAM on his 1998 Compaq. ;-)

See though, what did I tell you? It's only Poser. It's always only Poser.

Whatever you do, don't overclock that 8800 GTS and try it with Poser. You wanna talk terrified? I never saw Poser move so quick before. So quick to crash, that is. ;-)
I tried it with Riva Tuner and the EVGA Precision Tool and got some nice benchmarks in 3D Mark and Half-Life 2 Lost Coast, and it seemed perfectly stable with all the other graphics apps I have, but Poser didn't like it one little bit.