mmmmm.   yeah, that's the thing, i really think.  over several years, i poked at a pretty large number of different 3d tools.  and they all required me to learn an interface totally different than what i knew.  when i started looking more closely, i found myself having an immense amount of respect for the designers of Poser and how easy they made camera manipulation and object manipulation.  and i really never expected to appreciate Poser's interface designers. 

that said, as i mentioned, the biggest shift for me has been internal and conceptual.  i'm just beginning to dream about modeling, which says i'm not only in the beginning of that shift, but that my brain is struggling with it.  lots of people find it incredibly easy.  i see people who are like, "oh, i just bought Zbrush and it's great!" and then post works of art i don't know if i could ever do.  my eye and hand are just not there.  Blender has a sculpt tool i'm sure is much more limited, but since i also see people post incredible stuff made with it, i know the problem is me. 

what are you using now?  i'm wondering if there's not a way to simplify it in whatever you're already using.