A few comments.

Currently there are some issues with the connection between Vue (any version including 7) and Poser Pro, these issue will be fixed in the next service release of Vue 7 (so they promise us), not sure they will be fixed for any other version of Vue.

Is general when you need extreme close-up shots of characters rendering in Poser will yield better results but it may cause some problems with consistent skin textures, so it may be better to render these shots in Vue also. Anything shot from some distance will look better when rendered in Vue (this includes interior shots), this is my opinion, some may disagree. Outside shots will always look better in Vue (i don't think anyone will disagree).

Many rooms and room construction kits exist for Poser, these can be set up in Poser and imported into Vue. For many shots you would like to keep the room simple as to focus on the characters. It is often better to suggest something being there with a simple texture than to actually have a model of it. Lighting should look real without actually being really projected from the actual light sources.

Anything on your character (like blood, wounds, tattoos) should be put on the character texture map and should not be added in post work. Post work should be limited to compositing pictures and adding text and icons, this can be handled by simple programs. Editing texture maps is a bit more complex and would require a paint program with proper layer systems.

In addition to Poser and Vue most people need some kind of story boarding program (although I do this with hand drawn paper sketches). Investigate this and think about some kind of director program, since you are bound to include short animations soon. When using a computer medium to tell a 3D comic story it is easy to mix the single shots of the story (which advance the story without having to fill all the gaps) with short animations (which create a feeling of dynamic action). Forget about paper output, that is so yesterday.

Keep in mind that even a short story needs many shots, each shot should be set up quickly and render in short time. Only a few big shots may require a bit more attention. There is story to be told and it is about the story, it is not a series a very detailed pictures. In real live when watching something you will focus on the action, the background is just a blur, in stories the action should get all the attention and detail, the rest just fills the background, unless the story is set in a specific location, then the location should be accurate and detailed.