Quote - I might be doing things the hard way...but do you have to manually apply the material to every mat area on the figure and then reselect the textures that were "underneath"?

Also, does this preclude the use of any skin shaders? Is there some way to easily combine the two?

You could Right click on the PoserSurface tab>select all Right click again>apply to all, then use a mat pose to restore eyes to normal, then go through and reselect skin textures for each part.. Or Right click>select all>copy and paste to similar regions, V4 & M4 they're numbered. If you are using skin shaders rather than texture maps you might try copying and pasting those into this material and wiring them into the shader in place of the "your texture here" image map.