Quote - ...Can anybody give me a clue as what's going on and how to fix it?   

Jeremy

Is this Vista?

I don't have Vista.. I avoid it like the plague right now.  But, some people say that installing Poser in its default "Programs" directory will cause problems in Vista because of the permissions that Poser needs to have available to it in that otherwise Vista "protected" directory.  So, they recommend installing Poser in a directory by itself, off the main root directory instead so as to avoid database/runtime access issues.

Could this be the case here?