I have Studio running in VirtualBox 2.1.4 under Linux without issue in a Windows 2000 VM.   I installed the Guest additions, and ticked the box to enable 3d acceleration.

Edit-there is one issue-the camera pan goes only down to the right-inconvenient.  ;) I don't use Studio much.

Studio used to run well under Wine(I haven't tried it in a while), so it should run under Darwine if you are on a Mac.

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