Attached Link: http://www.renderosity.com/mod/gallery/index.php?image_id=1876604

In order to obtain a good looking skin in Vue it takes a good amount of effort both in materials and light. The adjustments to both things must be done together. You can have a wonderful material with all settings just perfect but if you have a bad lighting, it just doesn't work. And vice-versa.

Take the example in the link above. For this image, I used SkinVue as a start but then I changed almost everything about it. I edited SkinVue functions and changed them all, both in skin, lips and eyes. This was done in synch with the light adjustment. That's an environment mapping atmosphere, with some extra point lights carefully placed. The light model is Global Radiosity, with some gain. To get to that image, I worked for several hours, although I had done several portraits before (check out my gallery). In all the portraits I made, I never used the exact same technique. For every new image, I start with what I learned before and try to progress a bit more.

So, my advise is to experiment with all sorts of things until you're satisfied. As you gain experience, it'll become easier. :-)