Poser Pro works pretty good with wine, so do Hexagon, DAZ Studio and Carrara 6 and 7 pro. Photoshop Elements 5 runs but shows a weird behavior after some time of use. PSP XI won´t work at all. I also wen´t back to Windows because you spent to much time getting things to work. I now use a dual-boot system to still be able to use the advantages linux has.