Put it this way: My V4 runtime is 24.5 GB and about 28,000 files. Obviously, that's less than half of 60 GB - but I can open Poser to a new doc in about 15 seconds. I'm having no problems with that at all.

OTOH, I'm not having pathing issues, either, and I have 18 runtimes. I prefer it this way in part because it's much more readily obvious what character an item of clothing is for etc.

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Hardware: AMD Ryzen 9 3900X/MSI MAG570 Tomahawk X570/Zotac Geforce GTX 1650 Super 4GB/32GB OLOy RAM

Software: Windows 10 Professional/Poser Pro 11/Photoshop/Postworkshop 3