The tric for the cloth room is to stay low poly, and avoid "useless" collitions.

What you can do is:

Make your clothing LOW RES, do the sim.

Export the "clothed obj", and only then subdivide when needed. For "stills".

Final adjustments can be made with the morph brush. (If needed.) 

For movies? ? ? Stay Low Poly.
It is the only real "speed improver."

Poser 1, 2, 3, 4, 5, 7, P8 and PPro2010, P9 and PP2012, P10 and PP2014 Game Dev
"Do not drive faster then your angel can fly"!