Actually the correct path would be

for XP   -     C:Program Files/Smith Micro/Poser 8

for Vista -   C:Program Files (x86)/Smith Micro/Poser 8

If poser is not on the C drive, then put whatever drive letter poser is on in place of C.

Where ever you put her, be sure that V4.2 resides in the main runtime of Poser, as she tends to act really weird if not installed there.

@MarkyP: don't mean to step on toes here but, I corrected you because this folder structure is a must if V4 is going to work right.  :O)

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AMD FX-9590 4.7ghz 8-core, 32gb of RAM, Win7 64bit, nVidia GeForce GTX 760

PoserPro2012, Photoshop CS4 and Magix Music Maker

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...and when the day is dawning...I have to say goodbye...a last look back into...your broken eyes.