Which version of Photoshop, assuming that's what you mean by Adobe? Painter 3 is pretty old, so it wouldn't be undult surprising if it had problems - did it ever work under Windows 7? Which version of Windows 7 - Pro and above have "XP mode" which allows you to install a copy of XP in a virtual machine, it might let you run Painter if it's flat incompatible with Windows 7. For Photoshop, have you tried deleting the files in WindowsPrefetch?