"I think it all goes back to what your comfortable with, and how your brian is wired." 

 I don't think that can be emphasized enough. 3d is not word processing. People may quibble about the benefits of MS Office vs Open Office or Mac vs PC for that matter but after a bit of use most can be reasonably productive and comfortable in any of them. 3D does IMO come down a lot to how your brain is wired. The strong likes and dislikes are simply too intense to be explained by the relatively small differences in GUI or metaphor. People might complain a bit about finding the 'X' key on a normal productivity application but the same situation on a 3d app has them throwing up their hands and declaring it unusable. That's why it's impossible to answer the constant requests for the "Best" application. If what everyone else considers the lowliest piece of crap works for you that that is the best application of all.

"Democracy is a pathetic belief in the collective wisdom of individual ignorance." - H. L. Mencken