I would run something like;
Advanced systemcare free (free) One click maintanace, just click the "care" button in the middle.
Glary utilities (free) One click maintanance on top of the screen.
Optional ; Ccleaner (free)

Install and run , in that order.

Just pay atention to Glary utilities as it "cleans" skype a little too good.
 

But you can uncheck those lines if needed.

The first 2 also have a lot of usefull tools to check Windows, memory etc.

System would be as good as new.

Very carefully check the "options" of a lot of installed programs.

Do you realy need all spyware inspectors? One can get? Running all the time?
Te first 2 , manually, once an evening, do the job quite well.

Good luck

Poser 1, 2, 3, 4, 5, 7, P8 and PPro2010, P9 and PP2012, P10 and PP2014 Game Dev
"Do not drive faster then your angel can fly"!