I've got a 4x5 Graphire and I'm perfectly happy with it. A bigger one would've been waste of money, 4x5 is just perfect at least for me. The difference between Graphire and Intuos is (if I've understood correctly) that not only does Intuos have more pressure sensitivity but it also has tilt sensitivity which Graphire doesn't have. However, I personally feel Intuos is more for professional use - if you're a hobbyist a Graphire will probably be good enough for you. It sure is for me :)