But CTRL Z works as an undo for those WTF moments.

BTW, I just downloaded the 2.5 short-cut/hotkey pdf and it seems most of the key ones aren't going to change. I do use C to centre myself on the 3D cursor a lot (recent learn) and what would I do with Ctrl E? All my Edge-loop menu options... and W? All the stuff you can do with mesh like remove doubles and stuff...

Yes, you can use a menu but they've even made the hotkeys work quicker by remembering which of your menu options you used last... like say you want to slice some edges... and you did K (for Knife) and used Knife (midpoints) before... it will make that the highlighted (selected) option again. A lot of hotkey-driven menus work like that. Incredible.

Monterey/Mint21.x/Win10 - Blender3.x - PP11.3(cm) - Musescore3.6.2

Wir sind gewohnt, daß die Menschen verhöhnen was sie nicht verstehen
[it is clear that humans have contempt for that which they do not understand] 

Metaphor of Chooks