wow!! no wonder it slows down . Way too many fonts. loose them.
one way of organizing fonts is to use them for one project, then remove them, and store it a folder in the project folder that you keep (i guess you keep whatever work that you do stored in individual folders along with their corresponding art work/documents.
thatw ay, if you need a font, and know you have used it before.. you can easily pick it up from the folder, and re-install it. Only to de- install after you finish use it.
Works wonders...