I see what you're saying. Sculptris is stuck at one resolution making it trickier to process models compatible with interactive media where as with res layers in the traditional way allows for dropping back poly count or evening baking onto lower res to get the 'sculpted' effect without all of the weight.

I guess the same could be said for traditional weight painting over 3D-specific painters as you have more control and more options to go backwards and correct your textures. =)

Dramaking,

Yeah, that was a quickie model....the ridges around the eyes were meant to be glasses frames but decided I didn't want the frames to be that thick so didn't color them in completely. =D

This one I did afterwards in Sculptris and Mod Tools. Where I  inset and flattened the eyes a bit more.