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For example, in my Twitter account I only add those who I respect, like and have a relationship. These are the factors: if I really know them, or if I truly like what they do. If not, I let them follow but not follow them. If I think they are adding everybody in the world, I report them for spam with no mercy.

Passing on a tip that was passed on to me...I use Topify to help with that.  It alerts me when I get new followers, and gives me their last 5 tweets, their demographics posted on their twitter page, and the option to block them straight from my email.  Plus, it keeps my email address private.

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Knowledge is knowing a tomato is a fruit. Wisdom is not putting it into a fruit salad.