**Tashar59, all motherboards with PCI-E slots (or agp if your going way back) can take any graphics card be it Nvidia or ATI...  when you start talking about SLI or Crossfire then it does start to get motherboard specific... some motherboards have Crossfire compatibilty, some dont. Some boards have SLI compatiblity, some dont. Some motherboards can support both techs....   Its only if your going to have 2 GFX cards then you have to start looking at your motherboard specs.

Anyways 2 cards are pointless, usually you never get the full power out of the second card, and its always better to have a single more powerfull card than 2 cheaper ones (unless you can find the 2 cheaper cards for a real steal !)

I hope this clears up any confusion you have ;)
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