Naked as the day he was born...

All memory 'optimisers' do is drop memory pages thereby seemingly 'freeing' up memory. If you need that stuff then it has to be paged back in from pagefile or memory mapped files. They can't do anything nor manage memory better than Windows does itself - they can't without rewriting the memory manager since that is all they're dealing with.

With regards your pagefile, I wouldn't worry. It'll be freed when required. If there was an inherant memory issue with Poser then I'm sure we'd know about it by now. Leave Windows to manage its memory as it sees fit, i.e. system managed pagefile(s) and leave the memory managers alone.