Comic Life would make things a lot easier for the balloons and page layout.
I often use a program called Intocartoon for a quick conversion to a comic look.
The attachment was done in a few minutes using Comic Life with the right frame being a quick conversion using Intocartoon with some small color and detail adjustments, and the left frame being a Poser render with balloon added. Detail isn't very good because of 600 px width.
D3D's !Toon script is helpful for a comic look inside poser, as is ZFlatten. Although ZFlatten has a problem in Poser 8 and PP2010, mentioned in another thread.
Just some ideas.
Bob