As Geep has show us, it's possible to some degree, and PhilC has his Clothibng Creator suite that works entirely within Poser to make several types of clothes.

But it's not what Poser is meant to do. You can hack and coerce and prod it and make it do a lot of things it was never intended to do... but often (although not always!) the results are as could be expected. It's like using the coffee machine to cook pasta.. sure it can be done.. but.. well...

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You just can't put the words "Poserites" and "happy" in the same sentence - didn't you know that? LaurieA
  Using Poser since 2002. Currently at Version 11.1 - Win 10.