Quote - Does scale have anything to do with some of the artifacts in some renders? With Poser as small as it is, I know that up scaling Poser content works/looks better in other apps.

Commonly not. Artifacts may be a result of jpeg compression. Or just a bad render setup. 
Raise "Pixel Samples" (6), "Post Filter Size" (4) and "Post Filter Type" (sync) to avoid render-artifacts.

---