The biggest difference to me has been the renderer gamma-correction. Whilst most people - the point-and-click crowd - find this "feature" more of an annoyance than a benefit, once you understand material/render gamma correction you will see this as a real boon.
To clarify, gamma correction at the software level has nothing to do with monitor settings: if you do a search on this topic, you will find a lot of misinformation on the topic. To my understanding, it's all about what sort of information Poser needs in order to process colour information correctly.
Not going into more detail than that... suffice it to say that those who have explored GC in terms of render quality have found this quite useful.

Monterey/Mint21.x/Win10 - Blender3.x - PP11.3(cm) - Musescore3.6.2

Wir sind gewohnt, daß die Menschen verhöhnen was sie nicht verstehen
[it is clear that humans have contempt for that which they do not understand] 

Metaphor of Chooks