I don't think the cloth room was any harder to understand, than how to get conforming clothing working for a custom morphed figure. (Which is still a lot of work, especially if I want clothing to look natural)

Anything that's more advanced than slapping some clothing unto a basic, unmorphed figure takes some figuring out. Take the material room...

What could be greatly beneficial for newbies would be a clothroom wizard.  Can probably be done as a python script based tutorial.   It can lead the user through the basic steps of the cloth room.  Load or import the clothing, set a simulation, clothify and so on..   Could even add a more advanced tutorial on top of it to learn some more advanced features too, like how to use the different groups and so on.

As far as user interface goes, I don't know what would make it more accessible?