You might want to look at the NVida 570 or such. From what I've heard they improved the GPU used in the GTX 480 and made it run both better and cooler. I would stay away from the Quadra; I looked into the performance differences when I was building my office (spare bedroom really, but I can dream) system. I was able to get a GTX 480 and have enough left over for Photoshop rather than get a Quadra.