There's really not anything you can do in MD that you can't do by modelling on your own. MD may be good to speed up the initial process, but if you want really nice results after exporting to Poser or Daz, you still need to clean up the model, adjust the UV map so it suits your needs and so on.. 

And I personally find it really important to model certain faces in the right places. Like if you have seams, you want to have faces that match the seams. It -really- makes a difference in the cloth room. Just because it's easier initially to make dynamic clothing, it takes just as much work to make them look good as with conforming clothing.