If you can get a good deal on the advanced version (like when it was $1.88), and a few key plugins, it can be very useful to a developer or a heavy production user of Poser.  For example, with the Decimate plugin you can create reduced polygon versions of figures - handy for populating large environments and backdrops with a figure that may only be available for M4 or V4. With Aniblocks you can quickly create complex animations and then save them out as poses usable in poser, and even make new aniblocks sequences.  The down side is that these plugins both cost extra (around $60 or so each when not on sale).

If you are just using it for casual use, it all depends on your preferences.  There are people on both sides, some like Poser better, some like DS better.  Poser has more initial features packed in it from the go, but is slightly higher priced.  There are many more Poser plugins and scripts out there that are overlooked by so many, and usually more reasonably priced than those for DS.  While DS has a better initial cartoon render, there are solutions for poser (Anime Studio Pro can load Poser scenes and renders nice cartoon effects - or create a batch script for Photoshop or Gimp to post process your render).  A lot of it is a matter of taste.

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