I too uninstalled and reinstalled and had the latest service release and the latest drivers. 

Then, when I got Poser Pro 2010 I thought my problems would be over.   But it happened a couple of times with PP2010 as well although not as frequently as before.   With Poser 8 I would end up saving after every single thing I did, it was ridiculous.

Conflicting installations of Flash Player cause this and Smith Micro was not aware and kept insisting it was our drivers.   You're not the only one with this problem.   Do yourself a favour and uninstall Flash Player and reinstall only from their site.