It's a bit like having the exposure set wrong on a camera - (or white balance, or f-stop) - then correcting it in your image-processing software. Why not have it right in the first place?

But, to be honest, it's a lot more than just setting Gamma Correction to 2.2 or whatever. The adjustments one has to make to legacy (or even recent) Poser materials makes the whole exercise a lot more complex than it should be.

Short answer? You are probably going to find your renders are going to look like poo when you set renderer GC on (to 2.2). So, don't, unless you want to invest the time to clean up your shaders and fix your lights.

The information on how to do all that is carefully squirreled away on these threads. You can get reasonably good renders with gamma correction on. And you can get decent renders with it off - many of us have learned to compensate for software design shortcomings, so yes, it is possible. :blink:

Monterey/Mint21.x/Win10 - Blender3.x - PP11.3(cm) - Musescore3.6.2

Wir sind gewohnt, daß die Menschen verhöhnen was sie nicht verstehen
[it is clear that humans have contempt for that which they do not understand] 

Metaphor of Chooks