Quote - The things that really bug me about people saying render single frames out is this: First you have to learn yet another program and then do the extra work to do not only build the animation in that program but you also have extra work to sync up any audio you used. Unless you're making a movie for some major feature film project, which would mean using Poser is counter productive to begin with, you're better off rendering to your animation file in Poser with your audio track already loaded. That's this animators opinion.

The definitive determinant of whether you render to single frames or not, is can you reliably render the whole animation without Poser crashing.
Once you get close to the answer No, then you really don't have much choice about using other software, as splitting up an animation into chunks will require assembling them later.