Revisiting this thread, only because I've finally had the "a-HA!" and want to share it. Well, it was given me by KobaltKween, when I finally started listening to her.

First, my views on re-vamping the interface hasn't changed. It still needs that doing.

However, thanks to KobaltKween, I sort-of got a bit of a magic bullet ... or better put: a workable starting point for any and all cloths you might want to clothify. I didn't have that: a good starting point. So, with KobaltKween's permission, I'd like to share this with you. This is the short, quick version.

When starting with dynamic cloth, you want to start easy. The first poses to try might be ones where the figure doesn't work the cloth too much.

--So, have your figure in a standing sort of pose, for a dress, for example. That way, the dress only collides with the figure and doesn't have a lot of bending and stretching to do.

--Make sure that the cloth does not intersect with the figure anywhere.

--Load your figure (say, V4) and pose her in either the default zeroed pose using the joint editor, or using whatever the cloth maker provided for zero-pose.

--Check that your figure isn't translated anywhere from 0. Also, to start with, all morphs need to be set to zero, including custom morphs. They do come back, including expressions, in the final frame.

Let's say we use the default 30 frames. Go to frame 30 and make it a key frame. Pose your figure.

• In frame 1, load the cloth to be clothified on your zeroed figure. There should be no poke-through anywhere.
• In Cloth room, set up a new sim. Click on New Simulation...
• For Simulation Name I tend to call it by what I'm clothifying: short version. The only other change I make in this dialogue is to tick the Cloth self-collision tickbox... and Ok.
• Cloth Objects, click on Clothify... oftentimes your item will be selected. Click Clothify.
• Colide Against: click on the Add/Remove button and select your (V4) figure. Set collision Offset to 0.25 and Collision Depth to 0.2. These settings have worked an absolute treat for me for the past few days for all sorts of dynamic, hybrid and even conforming cloth that I've clothified, so I share them with you (thank you AGAIN!, KobaltKween!). Please keep in mind your mileage may vary.
  Tick Ignore head, hand and feet collisions, and click okay.
• Click Calculate Simulation.

I've had reasonably good success using just this quick, simple approach. It is an excellent starting point for those who are - like me - affected by rubbish output time after time and who just need a starting point.

Here is an example of what is possible after only two days of mucking with this:

Monterey/Mint21.x/Win10 - Blender3.x - PP11.3(cm) - Musescore3.6.2

Wir sind gewohnt, daß die Menschen verhöhnen was sie nicht verstehen
[it is clear that humans have contempt for that which they do not understand] 

Metaphor of Chooks