Like Onnetz said, it's likely that all available memory is being used and can't work with that additional texture. What I've done to fix that in the past is take the textures (image files) into photoshop (or GIMP or whatever) and scale them to half size and save as a copy. Unless you're doing a render of a blemish, you'll probably hardly be able to appreciate much difference.

Monterey/Mint21.x/Win10 - Blender3.x - PP11.3(cm) - Musescore3.6.2

Wir sind gewohnt, daß die Menschen verhöhnen was sie nicht verstehen
[it is clear that humans have contempt for that which they do not understand] 

Metaphor of Chooks