Never done it myself but it was interesting to check it out. The trick seems to be making sure you get exactly the right board with the right revision to match the old one. (40USD seems cheaper than +1000USD) Apart from that its just undo a few screws and mini block connectors.

Are HD warrantys going back up? Used to be 3yrs when I first made PCs but dropped to 1yr a few years ago when one of the majors had a vast amount fail.

Poser 11 , 180Gb in 8 Runtimes, PaintShop Pro 9
Windows 7 64 bit, Avast AV, Comodo Firewall
Intel Q9550 Quad Core cpu,  16Gb RAM, 250Gb + 250Gb +160Gb HD, GeForce GTX 1060