I have used the Quadro 37xx in my BOXX system for a year. Works flalesslyin Poser Pro 2010 and Vue 9 and 9.5 as well as mudbox and maya 2010. I spent the money on speed and stability. my old system with twin 8800gt's ran so hot it was very unreliable on a 5 day animation job or just because it would overheat and crash. I am partial to Nvidia but I really do like this card.