Why should the scaling be broken? I assume that LoD and the low-poly base won't work since Poser still don't have Catmull-Clark subdivision, but weightmaps and animatable joint centers are available. 

A ship in port is safe; but that is not what ships are built for.
Sail out to sea and do new things.
-"Amazing Grace" Hopper

Avatar image of me done by Chidori.