You could also unlink all of your old runtimes. Then create a few new ones and just reinstall content (in an organized manner) as you actually use it.

I've got 130GB in 13 runtimes, and a very gradual and continual reorgnization is the only way I can cope with it. I also find P3dO Explorer to be very useful. But much of the old content is no longer installed. If I find a need to use a Poserworld historial costume for M2, for example, then I'll make a Daz generation 2 runtime and install the stuff. Until then, it can stay zipped and tagged in my Poserworld>M2>Clothing folder.

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PoserPro 2014, PS CS5.5 Ext, Nikon D300. Win 8, i7-4770 @ 3.4 GHz, AMD Radeon 8570, 12 GB RAM.