I have 13 or so runtimes, containing something like this:

Gen 4: Generation 4 Daz figures, character textures, and hair

Gen 3: Likewise, only Generation 3

Gen 4 Clothing (needs to be split into male and female, now)

Gen 3 Clothing

Kids

Toons

Creatures

Other humanoid figures

Miscellaneous Props

Props and Scenes

 

You could organize things however you want. The main thing is that I always unzip (or instal, if a Daz product) the files to a dummy runtime first so that I can look at the file structure and rename folders, if I need to.

The renaming of folders is key to my sanity. If I later come across a structure such as

Runtime>Libraries>Pose>4Mp7yal>Characters>Bountiful>V4

I may have no idea what on earth it is. But if I rename the folders to:

Runtime>Libraries>Pose>V4 Clothing>Fantasy>Bountiful for So and So's Fantasy Wrap...

I'll know exactly what it is, where to find it, and whose clothing figures the MAT poses refer to.

You just have to be careful not to rename geometry, morph, or texture folders that will be referenced in the files themselves -- unless you want to edit the paths. But folders in the actual libraries (Pose, Props, Character, Hair, Light, Face, Hand, Cameras, and Materials categories of the library) can be renamed whatever you like.

I move all readme's and licenses to one folder at the top of the runtime. If I feel like renaming them, I do.

Some vendors have a habit of putting all of their work into folders using their own name:

Runtime>Libraries>Props>Kool3DKid>Scifi Mega City...

...which is great if you can remember who made what. If you're a fan and have multiple products for them, it's a good system. I do this for Stonemason, for instance. But for single products, it's a pain in the rear. So I would rename the props folder to read:

Runtime>Libraries>Props>Sci Fi>Urban Exterior>Scifi Mega City - Kool3DKid

If there were any MAT poses that went with the set, I'd keep as much of the file structure identical as I could:

Runtime>Libraries>Pose>Sci Fi>Urban Exterior>Scifi Mega City MAT - Kool3DKid

Finally, runtimes that I don't use much, aren't added to Poser. They still sit on the harddrive ready to use, but I don't force Poser to load them every time.

Oh, and one last point: There's no need to waste days of your life on a content installing frenzy reinstalling everything you own. Just re-install what you need for your next project.

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PoserPro 2014, PS CS5.5 Ext, Nikon D300. Win 8, i7-4770 @ 3.4 GHz, AMD Radeon 8570, 12 GB RAM.