The Data and Runtime folders need to be directly under the folder you've specified as a content folder (DS-format and Poser-format).  The People folder and its subfolders can be renamed and moved around as you like, but Data and Runtime must be first-level subdirectories of folders specified as content folders in Content Directory Manager.  The defaults would be "...DAZ 3D/Studio/My Library" for DS4 and "...DAZ 3D/Studio3/Content" for DS3.