All I have is AMD, and processing power and GPUs were no issue (at least with up to date drivers). No documentation, a craptastic UI, a functional lack of dynamics (if I have to buy a separate program, which -also- has a UI that is....poorly designed, shall we say? to get dynamic hair, and a plugin that restricts my dynamic cloth to whatever the the parent company deigns to provide and little else, then the features don't functionally exist), and a continuation of 3 previous never-got-out-of-beta versions development plan. Those were the big issues regarding DS4 imnsho. The genesis figure system has potential, but as long as it is bound to their app, and forces you to find some way to make it work if your system doesn't like it, then frankly it is largely a non-starter for the Poser-centric crowd.

 

Which is proving to be a good thing, as said crowd is rediscovering that 'old' does not mean 'useless'. That the past 15 years of content can be brought to a functional standard that lets them stand together in the same scene and not look out of place.