MD clothes work great in Poser's cloth room too. I would only retopo them if i would need to make them conforming. The cloth is created from seemingly irregular triangles, which behave great in the cloth simulation. The simulator from MD is much faster than Poser's though, so Poser's cloth sim is not my favorite way to go with MD cloth.

The software is dead easy to use, IMHO. There is a fully functional 30-day demo, so everyone can see if the software works for him/her. You can test it with a lot of demo clothes from their website. They have a lot of free clothes there which can easily fitted to any figure within MD.

 

A ship in port is safe; but that is not what ships are built for.
Sail out to sea and do new things.
-"Amazing Grace" Hopper

Avatar image of me done by Chidori.