with either medium, the larger you raiese the print's size, the quality shall be sacrificed. With analog, the best 35mm film you can buy in terms of photo qualty and the ease of enlarging with out losing detail is 100ASA film, or lower. The less grain there is, the faster the grain will react to light. ASA100 has a LOT of grain per 35mm picture, thus, when you enlarge, theres more detail held in place. Also, nothing, absolutely NOTHuing beats large format cameras in terms of quality.... as for digital, beats the fu#$ out of me... ry