Did you happen to get the System Fix virus? Everything on your desktop disappeared, your folders, etc?

If that's the case you need to run something called Unhide. I believe it's on mybleepingcomputer.com. If you do a search for "unhide.exe" you'll find it on their site. Run that and your software should now be able to find most everything and you'll be able to see most everything again as well.

Laurie